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Data indicate that dysfunctions of mechanotransduction mechanisms within the ganglion cell soma-dendrite, Mller cells and microglia may precede axonal degeneration, cupping of the optic nerve head and visual field damage which over the years have represented the golden standard of glaucoma diagnosis

(2024) reported that epileptic seizures can induce microglial activation and trigger a cascade involving the NOD-, LRR-and pyrin domain-containing protein 3 (NLRP3) inflammasome, leading to elevated pro-inflammatory cytokine levels, aggravated neuronal damage, and depression-like behaviors

hirsutum [13], Glycine max [35], and Solanum tuberosum [36]