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M.KitteringhamN.et al

In rat permanent MCA occlusion, infusion of ebselen, starting 45 min before and maintained 4 h after the occlusion, reduced cerebral cortical damage by 28%

Echinocandins are largely ineffective against Cryptococcus , and the efficacy of other agents is often compromised by host toxicity or fungal resistance (Denning, 2003) ( Supplementary File 1 )

Conversely, when oxidative challenges exceed physiological levels, they can disrupt redox signaling and cause oxidative damage to biomolecules, termed oxidative distress