![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Discovery of novel benzylaniline derivatives](https://ars.els-cdn.com/content/image/1-s2.0-S0223523421002087-ga1.jpg)
interaction of chloroacetamide electrophiles with cellular glutathion
interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Discovery of novel benzylaniline derivatives
Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Development of a Highly Selective Ferroptosis Inducer Targeting GPX4 with 2 Ethynylthiazole 4 carboxamide as Electrophilic Warhead Journal of Medicinal Chemistry Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS: Cell Chemical Biology
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![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Discovery of novel benzylaniline derivatives](https://ars.els-cdn.com/content/image/1-s2.0-S0223523425009547-ga1.jpg)
![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Discovery of novel benzylaniline derivatives](https://www.mdpi.com/biomedicines/biomedicines-10-00891/article_deploy/html/images/biomedicines-10-00891-g005.png)
![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Discovery of novel benzylaniline derivatives](https://pubs.acs.org/cms/10.1021/acs.jmedchem.4c02530/asset/images/medium/jm4c02530_0013.gif)
![interaction of chloroacetamide electrophiles with cellular glutathion Design, synthesis, and biological evaluation nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation Discovery of novel benzylaniline derivatives](https://www.cell.com/cms/10.1016/j.chembiol.2026.01.007/asset/e44364c4-658d-4195-bc7f-957b1fa35723/main.assets/fx1_lrg.jpg)