10.3892/mmr.2014.3079 Mol Med Rep
These canonical pathways have facilitated the analysis of large transcriptomic datasets, for example, exploring the effects of bariatric surgery on the activation of iron absorption pathways (Evers et al., 2022) or modeling macrophage iron sequestration during host defense against Aspergillus ( Approaches for other nutrient metals While the biophysical and biochemical characteristics of other nutrient metal cofactors differ from those of iron cofactors, the transient nature of the interactions between metallochaperones and client proteins is also characteristic of other metal distribution systems, making the methods described here suitable for the analysis of other metal trafficking systems
Nuclear factor-erythroid 2-related factor 2 (Nrf2) signaling pathway is the core mechanism of neurons resistance to ferroptosis, which can regulate the production of the key anti-ferroptosis enzyme glutathione peroxidase 4 (GPX4)
Br J Pharmacol 135(5):10791095 Esposito E, Di Matteo V, Benigno A, Pierucci M, Crescimanno G, Di Giovanni G (2007) Non-steroidal anti-inflammatory drugs in Parkinson's disease