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Studies on patients with ischemic stroke suggest that high circulating IGF-I levels are associated with neurological recovery and a better functional outcome[339], probably due to its neuroprotective and pro-angiogenic effects

Metformin treatment is also sometimes used for those who experience insulin resistance

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More detailly, omega-3 PUFA seems to modify its diversity by increasing the abundance of Bifidobacteria and Akkermansia as well as lowering Enterobacteria abundance [292]