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Metabolomic evidence for peroxisomal dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Viscosupplementation represents a middle-ground investment between temporary pain relief and major surgery

The presence of high serum bicarbonate could indicate chronic respiratory acidosis [typical of chronic obstructive pulmonary disease (COPD)] or metabolic alkalosis (secondary to vomiting, use of thiazide diuretics, or excess mineralocorticoids) (336)