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To view a copy of this licence, visit About this article Cite this article Kieliszek, M

Versaci F, Valenti V, Forte M, et al

Cytotoxicity profiling in vitro shows a dose-dependent pattern: cell viability holds within research-relevant concentration ranges but declines meaningfully above approximately 1 mM in culture, a threshold well outside the concentration windows described as biologically productive in the wound healing and gene expression literature

Functionally, GlyT1 occupies a central position in the interplay among glutamatergic, glycinergic, dopaminergic, and possibly other neurotransmitter systems, making it a relevant therapeutic target in a range of neurological and psychiatric conditions under active investigation (Sur and Kinney 2004, Harsing Jr et al