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With the increased emotional and physical stress, it is believed that the majority of the population has a degree of mitochondrial impairment that causes a cascading effect of inflammation and disease development

Otherwise, serum concentrations of vitamin B12 were found in a lower level in NAFLD cases compared with those of the controls in 75 Turks (13), and decreased vitamin B12 concentrations were significantly associated with an increased fibrosis grade, as well as non-alcoholic steatohepatitis in 83 cases in Israel (45)

Larger, placebo-controlled trials are necessary to better understand how B12 works in autism and which children benefit the most