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It also sits on a solid research base, with work exploring how it binds and signals at melanocortin receptors (Sawyer et al., 1980)

Al igual que en la mcula melantica labial se ha observado solamente aumento de la melanina a nivel del estrato basal

Esta pigmentacin es generalmente benigna y puede ser reversible al suspender el medicamento, aunque siempre debe hacerse bajo la supervisin de un mdico