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Results: Of 71 adults approached, 23 enrolled (15 acamprosate, 8 SOC), of which, 6 withdrew (2 acamprosate, 4 SOC) and 1 was lost to follow up (acamprosate)

Figure 6 3.5 CircRNA bioinformatics CircRNA (Circular RNA) has the characteristics of being abundant, evolutionarily conserved, and relatively stable in the cytoplasm, which enables it to have many functions and participate in gene expression regulation through various ways of action (21)