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Comparative pre-clinical safety research has documented a favourable profile for BPC-157 across multiple animal models and dosing conditions, contributing to its reputation as a well-tolerated research compound with a consistent experimental behaviour profile

Archived from the original on 5 December 2023

For example, cancer cells upregulate the expression level of the PPP [26] , NRF2 [52] , and isocitrate dehydrogenase 1 (IDH1) [48] as backup mechanisms for NADPH production