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A process that by now runs in a completely environmentally friendly way

Nevertheless, as our VBM study (31) employed a cross-sectional design, it is not possible to infer causality, and the possibility that structural brain abnormalities in the anterior insular cortex of early-onset smokers were pre-existing cannot be excluded

These results from our observational research need to be interpreted cautiously and be confirmed in future randomized clinical trials to overcome the limitations of lack of data from most recent years, the incomplete exposure measures and residual confounding effects, the researchers wrote

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