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Debris from a dead cell ANTIGEN- PRESENTING CELL Engulfing a spike Digesting proteins Presenting a spike protein fragment HELPER T CELL Debris from a dead cell ANTIGEN- PRESENTING CELL Engulfing a spike Digesting the proteins Presenting a spike protein fragment HELPER T CELL Debris from a dead cell Engulfing a spike ANTIGEN- PRESENTING CELL Digesting the proteins Presenting a spike protein fragment HELPER T CELL The cell presents fragments of the spike protein on its surface

Metformin , the first-line treatment for type 2 diabetes, is associated with reduced B12 levels in approximately 1030% of long-term users

Also, because B12 is a water soluble nutrient, it is not stored in the bloodstream and is easily excreted from the body

There is no receptor to desensitise on a fast clock, and no acute spike to time around a meal