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7 4) Example translational/clinical investigation Ipamorelin has also been investigated clinically as a ghrelinreceptor agonist in a phase 2 randomized proofofconcept study for postoperative ileus , where it was reported as well tolerated but did not significantly improve the primary efficacy endpoint versus placebo (as reported)

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Two areas of emerging research deserve particular attention: Non-HIV metabolic populations: Several investigators have studied tesamorelin in adults with abdominal obesity and metabolic syndrome, with consistent signals toward VAT reduction and improvements in liver fat in patients with non-alcoholic fatty liver disease

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