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A significant difference in calculated FS (%) was seen in sham rats with and without chronic tobacco exposure, and those with MI and chronic tobacco exposure demonstrated the most decrease in ventricular function

Sonic hedgehog-mediated epithelial-mesenchymal transition in renal tubulointerstitial fibrosis

For many researchers, the slightly lower efficacy is offset by fewer side effects and better day-to-day quality of life

Similarly, in diabetic mice, a PEGylated FGF21 analog increases the contribution of glucose to whole-body energy consumption, potentiating glycemic control without affecting body weight (285)