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youth has been attributed in part to the heavy marketing of these products with youth-resonating themes, as well as the widespread availability of youth-appealing flavors." In January, the National Academies of Sciences, Engineering and Medicine issued a report saying that e-cigarettes may be a less dangerous way to use tobacco, and may help established smokers reduce their immediate risk of death and disease, but they can hook teens and young adults and raise their risk of becoming smokers.

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At the same time, a growing proportion of total smokers use fewer than 10 cigarettes a day, said Neal Freedman, another NCI researcher involved in the study

Table 2: Maximum Likelihood Estimation: State Per Adult Cigarette Sales, 1990 - 2006 Notes: Statistical significance of 1%, 5% and 10% are represented by ***, **, and *, respectively