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however, commercially viable product titres have not yet been reached, partly due to issues arising from the late steps of the biosynthetic pathway 6,7

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To better understand events that occur during CRC formation and as part of the Human Tumor Atlas Network (HTAN) 7 , we performed transcriptome, proteome, metabolome and lipidome analyses of n = 93 samples from six persons with FAP (528 per person) representing different stages of cancer progression: unaffected colonic mucosa, benign polyps and dysplastic polyps