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Dysregulated nutrient-sensing

Mol Cell (2015) 58(2):20315

Essentially, methylmercury is thought to disrupt some of the cell signaling taking place when neurons are forming.[ref] The term Mad as a hatter referred to the neurological changes from long-term mercury exposure

compared with the first three months of the untreated period, the ALS Functional Rating Scale and BMI scores decreased significantly after three months of treatment, although the overall clinical benefit requires validation in larger-scale studies (145)