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doi: 10.1016/j.ibror.2017.03.001 295 WangG

Furthermore, the SIRT1 knockdown experiment demonstrates that the protective effect of IA against ferroptosis is partially abrogated, thereby reinforcing the notion that IA enhances mitochondrial function, inhibits myocardial lipid peroxidation, and alleviates ferroptosis via activation of the SIRT1 pathway [202]