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Bone marrow-derived mesenchymal stem cells ameliorate sepsis-induced acute kidney injury by promoting mitophagy of renal tubular epithelial cells via the SIRT1/parkin Axis

Nanobiotechnology 19 (1), 335

Building on this promising case report where anti-CD19 CAR T cells successfully treated a patient with severe SLE, Mackensen et al

First, the sulfonation reaction saturates and that allows more NAPQI to accumulate ([7, 24]) and second, the increased amount of NAPQI exhausts the liver stores of reduced glutathione (GSH)[6] as well as the livers capacity to synthesize new GSH