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Wernicke-Korsakoff in alcoholics Vitamin B2 (Riboflavin) Function: Energy production Deficiency signs: Cracks at mouth corners, sore throat, skin lesions Vitamin B3 (Niacin) Function: Metabolism, DNA repair Deficiency signs: Pellagra dermatitis, diarrhea, dementia Vitamin B6 (Pyridoxine) Function: Amino acid metabolism, neurotransmitter synthesis Deficiency signs: Irritability, depression, confusion, anemia Vitamin B12 (Cobalamin) Function: Red blood cell formation, nerve function Deficiency signs: Megaloblastic anemia, neuropathy, memory problems Folate (B9) Function: DNA synthesis, red blood cell formation Deficiency signs: Megaloblastic anemia, neural tube defects in pregnancy Fat-soluble vitamin deficiencies are less common but may occur in fat malabsorption

The risk of myelosuppression is increased in patients who do not receive vitamin supplementation