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Previous studies in myocardial ischemia have revealed that ischemia leads to a progressive loss of cholesterol from tissues and the sarcoplasmic and sarcoplasmic reticulum, accompanied by a significant increase in mitochondrial cholesterol content that is admixed explicitly to this membrane system [63]

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Since triple-negative breast cancer is difficult to control, ferroptosis initiation introduces a new method for the treatment of cancer cells with ACSL4 expression (Doll et al., 2017)

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