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For instance, kaempferol (a flavonol abundant in foods like saffron, apples, and leafy greens) protects against -synuclein toxicity: in PD models it increases neuronal viability, decreases misfolded -synuclein aggregates, prevents TH-positive neuron loss, and attenuates astrocyte activation (as indicated by reduced glial fibrillary acidic protein, GFAP) (19)