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Binding and neutralisation activity before and after spraying was maintained, highlighting the suitability of this platform for nasal delivery of monoclonal antibodies

This sets the stage for future investigations aimed at uncovering the complete spectrum of Irisins therapeutic potential in PD, ultimately leading to more effective treatment strategies

M.ImK.BelleS

Subsequent studies demonstrated that pretreatment with the eNOS inhibitor L-NAME resulted in a reduction in NO production in human umbilical vein endothelial cells (HUVEC)