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Translation to oral administration or to human physiology is unknown

30,37 They are corticosteroid-sparing agents that are thought to reduce T-cell function

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TARGETS OF PHARMACOTHERAPY IN THE MANAGEMENT OF OBESITY Novel insights provided by pathophysiology indicate the presence of a complex homeostatic system in which information about the energy reserve status and the meal quality and content is relayed from the periphery (gastrointestinal tract, pancreas, and adipose tissue) via specific orexigenic and anorexigenic peptides and hormones to the central nervous system (CNS)