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Moreover, Ashwagandha exhibits notable therapeutic synergy by potentiating the effects of radiation therapy through lowering tumor glutathione (GSH) levels, mitigating paclitaxel-induced neutropenia, and potentially enhancing immune function by promoting the generation of cytotoxic T lymphocytes [60, 221,222,223]

It was initially rejected in favor of the structurally related phenacetin, as it was considered too toxic

(Aspirins anti-inflammatory mechanism may be through HO-1.) One key effect of this little-considered enzyme is inflammation modulation together with anti-oxidative, anti-apoptotic functions and homeostatic functions

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