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Xu et al., 2015, 2021a)

Ebina M, Shimizukawa M, Shibata N, Kimura Y, Suzuki T, Endo M, et al

We therefore hypothesize that the observed disorder in nucleotide metabolism, marked by altered levels of S-adenosylmethionine and uracil, may be associated with enhanced gallbladder epithelial cell turnover and inflammation, thereby fostering a local microenvironment conducive to stone formation