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CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance Frontiers Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice Scientific Reports 5 amino 1mq and cd38 inhibitor combination benefits Comment curious for the full newsletter. There's a new metabolic regulator making waves. In preclinical studies, it: grip strength ~40%, muscle size, 5 Amino 1MQ blocks an enzyme called NNMT, and the mechanism is real, but NNMT overexpression does not track body fat. It tracks insulin resistance. Non diabetic individuals at BMI 33 had normal NNMT. And
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