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Taken together, these data support the proposed mechanism of action, i.e., IMC-M113V-mediated T cell activation upon specific engagement with pHLA complexes on Gag-expressing cells, with IL-6 secretion by myeloid and/or stromal cells occurring as a downstream effect

Some children with NF1 have symptomatic optic nerve gliomas and these may require treatment with chemotherapy and/or surgery

Chest x-rays can reveal hyperinflation (increased lung size), flattened diaphragms, and decreased lung markings, which may suggest emphysema

Glutathione also helps to reduce oxidative stress and inflammation, promoting a youthful complexion