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Because previous studies have demonstrated that NAD + depletion can induce cellular senescence, while the senescence associate secretory phenotype (SASP) in turn can induce CD38 26,27 , it was important to examine the impact of Ab68 on p21, a widely used albeit non-specific marker of cellular senescence

295 They established the copper-lactylated METTL16-FDX1-cuproptosis axis as a crucial regulatory mechanism in copper-related metabolism, filling a significant gap in our understanding of cuproptosis regulation

The results showed that the MM-GBSA binding energy using fastDRH ranged from 31.22 to 22.6 kcal/mol, with a variation similar to that obtained by the Glide energy and the MM-GBSA using Prime

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