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To advance clinical application, future research should develop multimodal biomarker panels by integrating technologies such as mass spectrometry imaging, spatial transcriptomics, and single-cell lipidomics, combined with artificial intelligence to define a distinct ferroptosis signature in neurodegeneration

Mucosal immune environment in colonic carcinogenesis: CD80 expression is associated to oxidative DNA damage and TLR4NFB signalling

Three nonoverlapping fields per section were imaged, and the protein expression intensity was quantified as the mean optical density (MOD) using ImageJ software (version 1.52)

They also manifested severe neurologic dysfunction and generalized aminoaciduria