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In addition, we found that NAC treatment prevented THC-induced increases in the polyamine spermidine, which is known to regulate glutamatergic signaling by potentiating NMDA-receptor sensitivity to glycine [105]

These findings might explain what we observed in this study, as the glucose metabolism increases, and as the Akkermansia is able to repair the intestinal wall, we observed a decreased level of inflammatory markers within the CNS, possibly due to decreased leaked from the gut 24,52,54,56

Protective activity of the stem bark aqueous extract of Musanga cecropioides in carbon tetrachloride- and acetaminophen-induced acute hepatotoxicity in rats

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