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doi:10.1093/bioinformatics/btp352 Lisowsky, T

Subsequent studies revealed that ArfGAP1 gene silencing rescues the inhibition of neurite outgrowth induced by G2019S LRRK2 in rodent primary cortical neurons, whereas co-expression of wild-type LRRK2 and ArfGAP1 synergistically promotes neurite outgrowth deficits [16, 17]

Some natural cell membranes such as exosomes without any functionalization have ability to cross the BBB

Acetylcysteine probably protects the liver by maintaining or restoring the glutathione levels, or by acting as an alternate substrate for conjugation with, and thus detoxification of, the reactive metabolite