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Given that our research primarily centers on the incidence of tumors, four tumors with the highest incidence rate were included and analyzed, including breast (morbidity: 11.7% of total cases

However, overexpression of Pfkfb3 activates glycolysis in neurons through the APC/C-Cdh1 pathway, which inhibits the pentose phosphate pathway (PPP), reduces the oxidation of glucose-6-phosphate (G6P), decreases the production of reduced glutathione, and finally leads to oxidative stress and apoptosis (Herrero-Mendez et al., 2009)

Once daily administration of Depakote ER in pediatric patients (10-17 years) produced plasma VPA concentration-time profiles similar to those that have been observed in adults

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