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Key Takeaway: Topical application alone faces bioavailability limitations

Transcriptomics analysis of mice treated with anwuligan, complemented by cellular validation, demonstrated that anwuligan induces upregulation of Ctnnb1 expression, activates the Wnt/-catenin signaling pathway, promotes the proliferation of hair follicle stem cells (HFSCs), and facilitates the progression of the hair follicle cycle

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