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found that another amino acid transporter, SLC25A22, could promote Asp synthesis, activate the AMPK pathway and reduce oxidative stress in KRAS mutant colorectal cancer (CRC) cells (Fig

Lee HK, Vaporciyan AA, Cox JD, Tucker SL, Putnam JB Jr, Ajani JA, Liao Z, Swisher SG , Roth JA, Smythe WR, Walsh GL, Mohan R, Liu HH, Mooring D, Komaki R