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Patients were randomized to receive pemetrexed 500 mg/m 2 intravenously or docetaxel 75 mg/m 2 as a 1-hour intravenous infusion once every 21 days

This mixed-salt formulation is widely used to simulate natural salt-alkaline soil conditions in controlled experimental setups, where neutral salts (NaCl, Na 2 SO 4 ) provide ionic background, and bicarbonatecarbonate salts (NaHCO 3 , Na 2 CO 3 ) are primarily responsible for elevating pH

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