glutathione imbalance reductase removal of reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging | Archives Toxicology Frontiers 9 Health Benefits of Glutathione

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Dobreva, A

If the trial had low risk for all domains, a high-quality study was considered a low risk of bias

In elderly individuals, circadian rhythms as well as sleep-wake regulation are weakened, leading to phase advances, decreased ability to adjust to phase shifts, and reduced amplitude of circadian rhythms (Duffy et al., 2015)