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Preliminary data from the studies reviewed here indicates that these products have the potential to be safe and effective

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Irrespective of their poor chemical reactivity, superoxide radicals are probably capable of interacting directly with specific intracellular targets as well as generating secondary cytotoxic species such as peroxynitrite (ONOO-) (7), which is formed via rapid radical-radical coupling reactions between O2- and nitric oxide (NO) in the vascular wall