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This finding linked selenium directly to thyroid function , metabolism, and energy regulation

10.1016/j.tiv.2019.104639 46 KanovaM.KohoutP

42 Topiramate is thought to act on the prefrontal cortex 18 and to exert its effects on the dopaminergic pathways from the ventral tegmental area to the nucleus accumbens, by enhancing GABAergic neurotransmission and antagonizing glutamatergic transmission, thereby leading to a decrease in dopamine in the nucleus accumbens

Acknowledgements This research was supported by the Ministry of Trade, Industry & Energy (MOTIE), Korea Institute for Advancement of Technology (KIAT) through the Encouragement Program (P0006145) for The Industries of Economic Cooperation Region