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doi: 10.3390/ijms23042342 110 LeeH-RYooS-JKimJParkCKKangSW

Senek M, Nielsen EI, Nyholm D

As the pool of the available GSH molecules is fixed, any unexpected increase of its utilization leads to a decrease of the free molecules and impairment of the competing pathways

Cytokine secretion by the skeletal muscle involves several intracellular factors such as MCP-1, heat shock factor (HSF)-1, and histone deacetylases, besides nuclear factor of activated T cells and NF-B [53, 61, 76, 80, 81]