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The assumption is that the CSI will reduce pain to allow more effective rehabilitation, but in fact the opposite may be true CSI may delay or reduce outcomes from a successful active intervention

[DOI] [PMC free article] [PubMed] [Google Scholar] 168.Yang D, Xia X, Xi S

and Cowey, C.B

Thus, cells have diverse mechanisms of mTORC1 activation for glutamine, and cancer cells efficiently utilize glutamine for mTORC1 pathway activation to drive unrestrained oncogenic growth