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eligibility typically requires a BMI of 35 kg/m or above (or 30 kg/m or above in certain ethnic groups), though thresholds vary by ICB Bariatric surgery referral for eligible patients, typically those with a BMI of 40 kg/m or above, or 35 kg/m or above with significant obesity-related comorbidities, in line with NICE guideline CG189 Structured diabetes prevention programmes for those at risk of type 2 diabetes These pathways offer genuine, monitored, and legally sanctioned routes to improved metabolic health

[DOI] [PubMed] [Google Scholar] 133.Pereira M.N., Ushirobira C.Y., Cunha-Filho M.S., Gelfuso G.M., Gratieri T

G., Lacolley, P

For example, in a clinical study (Clinical Trials identifier: NCT00322153), 28 mg of MEM were administrated daily orally for 24 weeks [107]