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Description

In such a model, multiple binding motifs on the same receptor, each with weak intrinsic affinity, would act in concert to increase the effective receptor protein concentration and thus support high-affinity binding to multimerized LC3/GABARAPs (Llus Garcs et al, 2009

Critically, we identified that the majority of SUMOylated proteins deregulated in CCA were involved in cell proliferation, survival or cell homeostasis