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The same study also reported that mature oligodendrocytes tended to concentrate in the 2040 micron annulus of amyloid plaques, whereas OPCs mostly abound at 1020 microns from plaques (Zeng et al., 2023)

10.5958/0974-4479.2019.00014.5 84 KhanM

Exacerbated esterification of arachidonic acid (AA) increases phosphatidylethanolamine-AA species which can be oxidized by lipoxygenase (LOX) leading to cell death by ferroptosis