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Reconstitution: Add 3.0 mL bacteriostatic water 166.7 mg/mL concentration Typical Range: 50100 mg taken 2-3 Times Per Week (gradual increase recommended) Measurement Guide: 1 unit (U-100 syringe) = 0.01 mL 1.67 mg Administration: Subcutaneous injection, once daily Storage: Lyophilized: Store frozen Reconstituted: Refrigerate (28C) and use within 14 days Dosing & Reconstitution Guide Educational guide for reconstitution and daily dosing Standard / Gradual Titration Approach (3 mL = 166.7 mg/mL) Frequency: NAD+ is typically administered 2-3 Times Per Week via subcutaneous injection

Curculigoside protects against titanium particle-induced osteolysis through the enhancement of osteoblast differentiation and reduction of osteoclast formation

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It has been demonstrated that the content of reduced ascorbate and glutathione in quiescent center cells is substantially decreased in comparison with cells located immediately above the proximal meristem, whereas the levels of oxidized forms of these compounds are substantially higher (Tables 1 and 2)