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Sequential anti-CD19 directed chimeric antigen receptor modified T-cell therapy (CART19) and PD-1 blockade with pembrolizumab in patients with relapsed or refractory B-cell non-hodgkin lymphomas

A number of data accumulated, demonstrating an association between cytotoxic T cell antigen-4 (CTLA-4), which is a major negative regulator of T-cell mediated immune functions, and autoimmune diseases including Hashimoto's thyroiditis

The remaining 10 mice were aged in the satellite until they reached 90-weeks of age, and were then studied in two groups, as old controls (OC, n = 5), and as old mice receiving a GlyNAC supplemented diet (OG, n = 5)

A subset of natural killer cells is greatly expanded within inflamed joints