glutathione cancer review Excessive intake contributes to chemotherapy resistance in breast cancer: a propensity score matching analysis | World Journal of Surgical Oncology Glutathione metabolism in cancer progression

doi:10.1007/s11940-019-0606-x Gaur S, Awasthi SK, Bhadouriya SK, Saxena R, Pathak VK, Bisht M

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Any alterations in the one-carbon cycle can, therefore, alter the genome methylation and influence the expression of vital genes involved in key mechanisms like angiogenesis, glucose metabolism, lipid metabolism, and neurodevelopment that will program the foetus for diseases in later life. 3 These diseases may result from: Impaired DNA synthesis and repair Changes in methylation that negatively change gene expression If there is a mutated MTHFR gene, the availability of active methyl folate is decreased

Genomics 298, 14791492