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Varinelli L, Guaglio M, Brich S, Zanutto S, Belfiore A, Zanardi F, Iannelli F, Oldani A, Costa E, Chighizola M, Lorenc E, Minardi SP, Fortuzzi S, Filugelli M, Garzone G, Pisati F, Vecchi M, Pruneri G, Kusamura S, Baratti D, Cattaneo L, Parazzoli D, Podesta A, Milione M, Deraco M, Pierotti MA, Gariboldi M (2023) Decellularized extracellular matrix as scaffold for cancer organoid cultures of colorectal peritoneal metastases

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Les scientifiques du Luxembourg Institute of Health (LIH) dcryptent ici, chez la souris, ce mcanisme molculaire qui favorise l'activation du systme immunitaire humain : les lymphocytes T, ces globules blancs du systme immunitaire luttent efficacement contre les agents pathognes la condition que le gne Gclc soit correctement exprim dans la cellule

54 In addition, elevated plasma nonesterified fatty acid (NEFA) levels impaired the insulin-induced increase in IRS-1-associated PI3K activity, but no defect in Akt phosphorylation was observed