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Disclosures: Vivienne Nguyen: Nothing to Disclose 2259 ABLATION OF NEURONAL SENESCENCE ATTENUATES THE COGNITIVE DEFICITS OBSERVED IN A MOUSE MODEL OF TYPE C HE Kathryn Rhodes 1 Juliet Venter 1 Matthew McMillin 2 Sharon DeMorrow 3 , 1 The University of Texas at Austin, 2 Baylor College of Medicine, Temple, 3 University of Texas at Austin Background: Hepatic encephalopathy resulting from chronic liver disease (Type C HE) is associated with neurological dysfunction and hyperammonemia

That is, for each participant, GSH levels were estimated after correcting for partial volume effects in each voxel using the method proposed in Gasparovic et al(Gasparovic et al., 2018), and GABA levels were alpha-corrected(Harris et al., 2015), since metabolite levels are reported to differ between brain gray and white matter(Gong et al., 2022)